Wallace group

Our immune system protects us against infectious disease, but sometimes attacks our own cells, causing disease. Our group develop and apply statistical genomic methods to understand the genes, cells and pathways involved in disease development and response to treatment. We are particularly interested in methods that borrow information between related diseases and that integrate data across different datasets or omics layers. Our goal is to help elucidate the biological mechanisms underlying immune-mediated disease development and progression in order to help identify treatment targets and opportunities for drug repurposing.