Publications

2025

1. Outcome-guided spike-and-slab Lasso Biclustering: A Novel Approach for Enhancing Biclustering Techniques for Gene Expression Analysis Statistics and Computing
   Luis A. Vargas-Mieles, Paul D. W. Kirk, Chris Wallace

2. Design and interpretation of eQTL-GWAS colocalisation studies: lessons from a large-scale evaluation preprint
   Guillermo Reales, Jeffrey M. Pullin, Ichcha Manipur, Elena Vigorito, Chris Wallace

3. Systematic comparison of colocalization methods using protein quantitative trait loci preprint
   Seongwon Hwang, Jeffrey Pullin, Chris Wallace, John Whittaker, Stephen Burgess

4. Large-scale GWAS meta-analysis of serum antibody levels reveals distinct genetic architectures preprint
   Thomas W. Willis, Effrossyni Gkrania-Klotsas, Nicholas J. Wareham, Eoin F. McKinney, Paul A. Lyons, Kenneth G.C. Smith, Chris Wallace

5. Variable information across SNPs in GWAS data can cause false rejections of colocalisation which can be resolved by proportional colocalisation tests preprint
   Chris Wallace, Chloe Robins, Toby Johnson

6. Inflammation and Obesity Correlate in Pulmonary Hypertension but Associate with Diverging Outcomes American Journal of Respiratory and Critical Care Medicine
   Eckart De Bie, Priscilla Correa-Jaque, Rowena Jones, Harm J. Bogaard, Justine Chan, …, David G. Kiely, Raymond L. Benza, Alex Rothman, Chris Wallace, Mark Toshner

7. Flexible and efficient count-distribution and mixed-model methods for eQTL mapping with quasar preprint
   Jeffrey M. Pullin, Jarny Choi, Davis J. McCarthy, Chris Wallace

8. MDA5 variants trade antiviral activity for protection from autoimmune disease. BMC medical genomics
   Chris Wallace, Rahul Singh, Yorgo Modis

9. Performance of deep-learning-based approaches to improve polygenic scores Nature Communications
   Martin Kelemen, Yu Xu, Tao Jiang, Jing Hua Zhao, Carl A. Anderson, Chris Wallace, Adam Butterworth, Michael Inouye

10. Variant-specific priors clarify colocalisation analysis PLOS Genetics
    Jeffrey M. Pullin, Chris Wallace

11. Penalised regression improves imputation of cell-type specific expression using RNA-seq data from mixed cell populations compared to domain-specific methods PLOS Computational Biology
    Wei-Yu Lin, Melissa Kartawinata, Bethany R. Jebson, Restuadi Restuadi, Hannah Peckham, …, Claire T. Deakin, Coziana Ciurtin, CLUSTER Consortium, Lucy R. Wedderburn, Chris Wallace

12. Genetic coupling of enhancer activity and connectivity in gene expression control. Nature Communications
    Helen Ray-Jones, Chak Kei Sung, Lai Ting Chan, Alexander Haglund, Pavel Artemov, …, Chris Wallace, Valeriya Malysheva, Leonardo Bottolo, Elena Vigorito, Mikhail Spivakov

13. Cell-type-resolved genetic regulatory variation shapes inflammatory bowel disease risk preprint
    Tobi Alegbe, Bradley T Harris, Laura Fachal, Lucia Ramirez-Navarro, Marcus Tutert, …, Chris Wallace, Cristina Cotobal Martin, Gareth-Rhys Jones, Tim Raine, Carl A Anderson

14. Exploiting pleiotropy to enhance variant discovery with functional false discovery rates Nature Computational Science
    Andrew J. Bass, Chris Wallace

15. Identification and validation of interferon-driven gene signature as a predictor of response to methotrexate in juvenile idiopathic arthritis Annals of the Rheumatic Diseases
    Melissa Kartawinata, Wei-Yu Lin, Beth Jebson, Kathryn O’Brien, Elizabeth Ralph, …, Restuadi Restuadi, Elizabeth C. Rosser, Claire T. Deakin, Lucy R. Wedderburn, Chris Wallace

16. Semi-supervised Bayesian integration of multiple spatial proteomics datasets PLOS Computational Biology
    Stephen Coleman, Lisa Breckels, Ross F. Waller, Kathryn S. Lilley, Chris Wallace, Oliver M. Crook, Paul D. W. Kirk

2024

1. Bayesian clustering with uncertain data PLOS Computational Biology
   Kath Nicholls, Paul D. W. Kirk, Chris Wallace

2. CoPheScan: phenome-wide association studies accounting for linkage disequilibrium Nature Communications
   Ichcha Manipur, Guillermo Reales, Jae Hoon Sul, Myung Kyun Shin, Simonne Longerich, Adrian Cortes, Chris Wallace

3. A Genome-Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome Arthritis & Rheumatology
   Desiré Casares‐Marfil, Manuel Martínez‐Bueno, Maria Orietta Borghi, Guillermo Pons‐Estel, PRECISESADS Clinical Consortium, …, Pier Luigi Meroni, Javier Martin, Jason S. Knight, Marta E. Alarcón‐Riquelme, Amr H. Sawalha

4. A disease-associated gene desert directs macrophage inflammation through ETS2 Nature
   C. T. Stankey, C. Bourges, L. M. Haag, T. Turner-Stokes, A. P. Piedade, …, P. Skoglund, M. Z. Cader, C. Wallace, D. C. Thomas, J. C. Lee

5. Development and implementation of ‘A guide to PPIE - Early Integration into Research Proposals’ in a multi-disciplinary consortium Rheumatology
   Richard Beesley, Freya Luling Feilding, CLUSTER Consortium Champions, Richard Beesley, Sharon Douglas, …, Victoria Basey, Peyman Adjamian, Helen Neale, John Ioannou, Hussein Al-Mossawi

6. Discovery of new myositis genetic associations through leveraging other immune-mediated diseases Human Genetics and Genomics Advances
   Guillermo Reales, Christopher I. Amos, Olivier Benveniste, Hector Chinoy, Jan De Bleecker, …, Simon Rothwell, Albert Selva-O’Callaghan, Jiri Vencovský, Lucy R. Wedderburn, Chris Wallace

7. Integration of Genetic and Clinical Risk Factors for Risk Classification of Uveitis in Patients With Juvenile Idiopathic Arthritis Arthritis & Rheumatology
   Melissa Tordoff, Samantha L. Smith, Saskia Lawson‐Tovey, Andrew D. Dick, Michael W. Beresford, …, Andrew P. Morris, Stephen Eyre, Lucy R. Wedderburn, John Bowes, the CLUSTER Consortium

8. Leveraging pleiotropy identifies common-variant associations with selective IgA deficiency Clinical Immunology
   Thomas W. Willis, Effrossyni Gkrania-Klotsas, Nicholas J. Wareham, Eoin F. McKinney, Paul A. Lyons, Kenneth G.C. Smith, Chris Wallace

9. Polymorphic tandem repeats influence cell type-specific gene expression across the human immune landscape preprint
   Hope A. Tanudisastro, Anna S.E. Cuomo, Ben Weisburd, Matthew Welland, Eleanor Spenceley, …, Alex W. Hewitt, Gemma A. Figtree, Katrina M. de Lange, Joseph E. Powell, Daniel G. MacArthur

10. Towards stratified treatment of JIA: machine learning identifies subtypes in response to methotrexate from four UK cohorts eBioMedicine
    Stephanie J.W. Shoop-Worrall, Saskia Lawson-Tovey, Lucy R. Wedderburn, Kimme L. Hyrich, Nophar Geifman, …, Vasiliki Alexiou, Victoria J. Burton, Wei-Yu Lin, Wendy Thomson, Zoe Wanstall

11. shaPRS: Leveraging shared genetic effects across traits or ancestries improves accuracy of polygenic scores The American Journal of Human Genetics
    Martin Kelemen, Elena Vigorito, Laura Fachal, Carl A. Anderson, Chris Wallace

2023

1. Accurate detection of shared genetic architecture from GWAS summary statistics in the small-sample context PLOS Genetics
   Thomas W. Willis, Chris Wallace

2. BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing Bioinformatics
   Elena Vigorito, Anne Barton, Costantino Pitzalis, Myles J Lewis, Chris Wallace

3. Sharing GWAS summary statistics results in more citations Communications Biology
   Guillermo Reales, Chris Wallace

4. A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2 preprint
   CT Stankey, C Bourges, T Turner-Stokes, AP Piedade, C Palmer-Jones, …, P Skoglund, C Wallace, MZ Cader, DC Thomas, JC Lee

5. Gene expression signature predicts rate of type 1 diabetes progression eBioMedicine
   Tomi Suomi, Inna Starskaia, Ubaid Ullah Kalim, Omid Rasool, Maria K. Jaakkola, …, Bart Eeckhout, Bernard Peene, N. Vantongerloo, Toon Maes, Leen Gommers

6. Shared and distinct molecular effects of regulatory genetic variants provide insight into mechanisms of distal enhancer-promoter communication preprint
   Helen Ray-Jones, Zeji Song, Lai Ting Chan, Alexander Haglund, Pavel Artemov, …, Chris Wallace, Valeriya Malysheva, Leonardo Bottolo, Elena Vigorito, Mikhail Spivakov

7. The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource Pediatric Rheumatology
   Saskia Lawson-Tovey, Samantha Louise Smith, Nophar Geifman, Stephanie Shoop-Worrall, Sandra Ng, …, Jacqui Roberts, Rami Kallala, Helen Neale, John Ioannou, Hussein Al-Mossawi

2022

1. Probabilistic classification of anti-SARS-CoV-2 antibody responses improves seroprevalence estimates. Clinical & Translational Immunology
   Xaquin Castro Dopico, Sandra Muschiol, Nastasiya F Grinberg, Soo Aleman, Daniel J Sheward, …, Gordana Bogdanovic, Ben Murrell, Jan Albert, Chris Wallace, Gunilla B Karlsson Hedestam

2. Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine
   Rowena J. Jones, Eckart M. D. D. De Bie, Emily Groves, Kasia I. Zalewska, Emilia M. Swietlik, …, Rob V. Mackenzie Ross, Jay Suntharalingam, Mark Grover, Ali Kirby, Richard Trembath

3. Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches The American Journal of Human Genetics
   Verena Zuber, Nastasiya F. Grinberg, Dipender Gill, Ichcha Manipur, Eric A.W. Slob, Ashish Patel, Chris Wallace, Stephen Burgess

4. Consensus clustering for Bayesian mixture models BMC Bioinformatics
   Stephen Coleman, Paul D. W. Kirk, Chris Wallace

5. Genome-wide association study of longitudinal urinary albumin excretion in patients with type 1 diabetes preprint
   Anna M Hutchinson, Wei-Min Chen, Suna Onengut-Gumuscu, Paul Benitez-Aguirre, Fergus J Cameron, …, Sally M Marshall, Andrew Neil, Stephen S Rich, M. Loredana Marcovecchio, Chris Wallace

6. High-resolution promoter interaction analysis in Type 3 Innate Lymphoid Cells implicates Batten Disease gene CLN3 in Crohn’s Disease aetiology preprint
   Valeriya Malysheva, Helen Ray-Jones, Nora Lakes, Rachel A. Brown, Tareian A. Cazares, …, Eugene M. Oltz, Chris Wallace, Emily R. Miraldi, Stephen Waggoner, Mikhail Spivakov

7. INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes Trials
   David B. Dunger, Sylvaine F. A. Bruggraber, Adrian P. Mander, M. Loredana Marcovecchio, Timothy Tree, …, T. Maes, L. Gommers, M.L. Marcovecchio, J. Vela, E. Latres

8. Mendelian randomization Nature Reviews Methods Primers
   Eleanor Sanderson, M. Maria Glymour, Michael V. Holmes, Hyunseung Kang, Jean Morrison, …, Tom Palmer, C. Mary Schooling, Chris Wallace, Qingyuan Zhao, George Davey Smith

9. Use of MRP8/14 in clinical practice as a predictor of outcome after methotrexate withdrawal in patients with juvenile idiopathic arthritis Clinical Rheumatology
   Emma Jane Welsh, Beverley Almeida, Jason Palman, Peter Bale, Clare Heard, …, Simona Ursu, Chris Wallace, Kimberly Gilmour, Lucy R. Wedderburn, Elizabeth Ralph

10. fcfdr: an R package to leverage continuous and binary functional genomic data in GWAS BMC Bioinformatics
    Anna Hutchinson, James Liley, Chris Wallace

2021

1. The flashfm approach for fine-mapping multiple quantitative traits Nature Communications
   N. Hernández, J. Soenksen, P. Newcombe, M. Sandhu, I. Barroso, C. Wallace, J. L. Asimit

2. Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR PLOS Genetics
   Anna Hutchinson, Guillermo Reales, Thomas Willis, Chris Wallace

3. A more accurate method for colocalisation analysis allowing for multiple causal variants. PLOS Genetics
   Chris Wallace

4. Detecting chromosomal interactions in Capture Hi-C data with CHiCAGO and companion tools. Nature Protocols
   Paula Freire-Pritchett, Helen Ray-Jones, Monica Della Rosa, Chris Q. Eijsbouts, William R. Orchard, Steven W. Wingett, Chris Wallace, Jonathan Cairns, Mikhail Spivakov, Valeriya Malysheva

5. Detection of quantitative trait loci from RNA-seq data with or without genotypes using BaseQTL Nature Computational Science
   Elena Vigorito, Wei-Yu Lin, Colin Starr, Paul D. W. Kirk, Simon R. White, Chris Wallace

6. Accurate error control in high‐dimensional association testing using conditional false discovery rates Biometrical Journal
   James Liley, Chris Wallace

7. Comparison of sparse biclustering algorithms for gene expression datasets Briefings in Bioinformatics
   Kath Nicholls, Chris Wallace

8. EPISPOT: An epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies The American Journal of Human Genetics
   Hélène Ruffieux, Benjamin P. Fairfax, Isar Nassiri, Elena Vigorito, Chris Wallace, Sylvia Richardson, Leonardo Bottolo

9. Multi-tissue transcriptome-wide association studies Genetic Epidemiology
   Nastasiya F. Grinberg, Chris Wallace

10. RápidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset Bioinformatics
    Guillermo Reales, Elena Vigorito, Martin Kelemen, Chris Wallace

11. Seropositivity in blood donors and pregnant women during the first year of SARS-CoV-2 transmission in Stockholm, Sweden Journal of Internal Medicine
    X. Castro Dopico, S. Muschiol, M. Christian, L. Hanke, D. J. Sheward, …, T. Allander, C. Wallace, B. Murrell, J. Albert, G. B. Karlsson Hedestam

2020

1. Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study. The American Journal of Human Genetics
   Lourdes Ortiz-Fernández, Güher Saruhan-Direskeneli, Fatma Alibaz-Oner, Sema Kaymaz-Tahra, Patrick Coit, …, Lindi Jiang, Justin C. Mason, Peter A. Merkel, Haner Direskeneli, Amr H. Sawalha

2. Patient-reported wellbeing and clinical disease measures over time captured by multivariate trajectories of disease activity in individuals with juvenile idiopathic arthritis in the UK: a multicentre prospective longitudinal study. The Lancet Rheumatology
   Stephanie J W Shoop-Worrall, Kimme L Hyrich, Lucy R Wedderburn, Wendy Thomson, Nophar Geifman, …, Emma Sumner, Damian Tarasek, Chris Wallace, Zoe Wanstall, Annie Yarwood

3. Genetic feature engineering enables characterisation of shared risk factors in immune-mediated diseases. Genome Medicine
   Oliver S. Burren, Guillermo Reales, Limy Wong, John Bowes, James C. Lee, …, Paul A. Lyons, Kenneth G. C. Smith, Wendy Thomson, Paul D. W. Kirk, Chris Wallace

4. Fine-mapping genetic associations Human Molecular Genetics
   Anna Hutchinson, Jennifer Asimit, Chris Wallace

5. Improving the coverage of credible sets in Bayesian genetic fine-mapping PLOS Computational Biology
   Anna Hutchinson, Hope Watson, Chris Wallace

6. BaseQTL: A bayesian method to detect eQTLs from RNA-seq data with or without genotypes preprint
   Elena Vigorito, Wei-Yu Lin, Colin Starr, Paul DW Kirk, Simon R White, Chris Wallace

7. Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses PLOS Genetics
   Chris Wallace

8. Resolving mechanisms of immune-mediated disease in primary CD4 T cells preprint
   C Bourges, AF Groff, OS Burren, C Gerhardinger, K Mattioli, …, MW Epping, C Wallace, KGC Smith, JL Rinn, JC Lee

2019

1. Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status. Nature Communications
   Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard M. R. Coulson, …, Richard A Watts, Augusto Vaglio, Julia U Holle, Chris Wallace, Kenneth G. C. Smith

2. Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy. The American Journal of Human Genetics
   Artika P. Nath, Scott C. Ritchie, Nastasiya F. Grinberg, Howard Ho-Fung Tang, Qin Qin Huang, …, Olli T. Raitakari, Veikko Salomaa, Gad Abraham, Johannes Kettunen, Michael Inouye

3. Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases Nature Communications
   Jennifer L. Asimit, Daniel B. Rainbow, Mary D. Fortune, Nastasiya F. Grinberg, Linda S. Wicker, Chris Wallace

4. Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters preprint
   Joanna Mitchelmore, Nastasiya Grinberg, Chris Wallace, Mikhail Spivakov

5. Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data Scientific Reports
   Alberto Romagnoni, Simon Jégou, Kristel Van Steen, Gilles Wainrib, Jean-Pierre Hugot, …, Michelle Ricketts, Matthew Waller, Paul Weston, Sara Widaa, Pamela Whittaker

6. Sharing information between related diseases using Bayesian joint fine mapping increases accuracy and identifies novel associations in six immune mediated diseases preprint
   Jennifer L Asimit, Daniel B Rainbow, Mary D Fortune, Nastasiya F Grinberg, Linda S Wicker, Chris Wallace

2018

1. Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks Nature Communications
   Mun-Kit Choy, Biola M. Javierre, Simon G. Williams, Stephanie L. Baross, Yingjuan Liu, …, Paula Freire-Pritchett, Peter J. Rugg-Gunn, Mikhail Spivakov, Peter Fraser, Bernard D. Keavney

2. Fine mapping chromatin contacts in capture Hi-C data preprint
   Christiaan Eijsbouts, Oliver Burren, Paul Newcombe, Chris Wallace

3. DNA methylation oscillation defines classes of enhancers preprint
   Emanuele Libertini, Rifat A. Hamoudi, Simon Heath, Lee Lancashire, Arcadio Rubio Garcia, …, Mikhail Spivakov, Peter Fraser, Antony Cutler, Chris Wallace, Stephan Beck

4. Genetically distinct clinical subsets, and associations with asthma and eosinophil abundance, within Eosinophilic Granulomatosis with Polyangiitis preprint
   Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard M.R. Coulson, …, Richard A Watts, Augusto Vaglio, Julia U Holle, Chris Wallace, Kenneth G. C. Smith

5. Improved consistency in estimates of conditional false discovery rates increases power relative to both existing methods and parametric estimators preprint
   James Liley, Chris Wallace

6. SimGWAS: A fast method for simulation of large scale case-control GWAS summarystatistics preprint
   Mary D. Fortune, Chris Wallace

2017

1. The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age. Diabetologia
   Jamie R. J. Inshaw, Neil M. Walker, Chris Wallace, Leonardo Bottolo, John A. Todd

2. Chromosome contacts in activated T cells identify autoimmune disease candidate genes. Genome Biology
   Oliver S. Burren, Arcadio Rubio García, Biola-Maria Javierre, Daniel B. Rainbow, Jonathan Cairns, …, Mikhail Spivakov, John A. Todd, Linda S. Wicker, Antony J. Cutler, Chris Wallace

3. Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2. JCI Insight
   Marcin L. Pekalski, Arcadio Rubio García, Ricardo C. Ferreira, Daniel B. Rainbow, Deborah J. Smyth, …, Alasdair J. Coles, Joanne L. Jones, Chris Wallace, John A. Todd, Linda S. Wicker

4. Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity. Journal of Autoimmunity
   Ricardo C. Ferreira, Henry Z. Simons, Whitney S. Thompson, Daniel B. Rainbow, Xin Yang, …, Anita Chandra, Chris Wallace, John A. Todd, Linda S. Wicker, Marcin L. Pekalski

5. A method for identifying genetic heterogeneity within phenotypically defined disease subgroups Nature Genetics
   James Liley, John A Todd, Chris Wallace

6. A rareIL2RAhaplotype identifies SNP rs61839660 as causal for autoimmunity preprint
   Daniel B. Rainbow, Marcin Pekalski, Antony J. Cutler, Oliver Burren, Neil Walker, John A. Todd, Chris Wallace, Linda S. Wicker

7. Type 1 diabetes genome-wide association analysis with imputation identifies five new risk regions preprint
   Nicholas J. Cooper, Chris Wallace, Oliver Burren, Antony Cutler, Neil Walker, John A. Todd

2016

1. A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies The American Journal of Human Genetics
   Corneliu A. Bodea, Benjamin M. Neale, Stephan Ripke, Mark J. Daly, Bernie Devlin, …, Michelle Ricketts, Matthew Waller, Paul Weston, Sara Widaa, Pamela Whittaker

2. Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters Cell
   Biola M. Javierre, Oliver S. Burren, Steven P. Wilder, Roman Kreuzhuber, Steven M. Hill, …, Alexander Kovacsovics, Laura Clarke, David Richardson, Avik Datta, Paul Flicek

3. Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial PLOS Medicine
   John A. Todd, Marina Evangelou, Antony J. Cutler, Marcin L. Pekalski, Neil M. Walker, …, Mark Evans, Adrian P. Mander, Simon Bond, Linda S. Wicker, Frank Waldron-Lynch

4. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery Cell
   Hendrik G. Stunnenberg, Sergio Abrignani, David Adams, Melanie de Almeida, Lucia Altucci, …, Stephen Yip, Jae-Il Yoo, Daniel Zerbino, Gideon Zipprich, Martin Hirst

2015

1. A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics PLOS Genetics
   James Liley, Chris Wallace

2. Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci Nature Communications
   Paul Martin, Amanda McGovern, Gisela Orozco, Kate Duffus, Annie Yarwood, …, Anne Barton, Chris Wallace, Peter Fraser, Jane Worthington, Steve Eyre

3. Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis Nature Communications
   John Bowes, Ashley Budu-Aggrey, Ulrike Huffmeier, Steffen Uebe, Kathryn Steel, …, Pauline Ho, Frank Behrens, Harald Burkhardt, Andre Reis, Anne Barton

4. Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping PLOS Genetics
   Chris Wallace, Antony J Cutler, Nikolas Pontikos, Marcin L Pekalski, Oliver S Burren, …, Stephen J Sawcer, Maria Ban, Sylvia Richardson, John A Todd, Linda S Wicker

5. Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing European Journal of Immunology
   Daniel B. Rainbow, Xin Yang, Oliver Burren, Marcin L. Pekalski, Deborah J. Smyth, …, Kim Brugger, Howard Martin, John A. Todd, Chris Wallace, Linda S. Wicker

6. Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers Nature Genetics
   Type 1 Diabetes Genetics Consortium, Suna Onengut-Gumuscu, Wei-Min Chen, Oliver Burren, Nick J Cooper, …, Panos Deloukas, John A Todd, Chris Wallace, Patrick Concannon, Stephen S Rich

7. IL-21 production by CD4⁺ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients Diabetologia
   Ricardo C. Ferreira, Henry Z. Simons, Whitney S. Thompson, Antony J. Cutler, Xaquin Castro Dopico, …, David B. Dunger, Chris Wallace, John A. Todd, Linda S. Wicker, Marcin L. Pekalski

8. Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases Human Molecular Genetics
   H. Guo, M. D. Fortune, O. S. Burren, E. Schofield, J. A. Todd, C. Wallace

9. Natural variation in interleukin-2 sensitivity influences regulatory T-cell frequency and function in individuals with long-standing type 1 diabetes Diabetes
   Jennie H.M. Yang, Antony J. Cutler, Ricardo C. Ferreira, James L. Reading, Nicholas J. Cooper, …, Christopher S. Boyce, Guo-Jian Gao, John A. Todd, Linda S. Wicker, Timothy I.M. Tree

10. Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls Nature Genetics
    Mary D Fortune, Hui Guo, Oliver Burren, Ellen Schofield, Neil M Walker, …, Jane Worthington, Anne Barton, Steve Eyre, John A Todd, Chris Wallace

11. Widespread seasonal gene expression reveals annual differences in human immunity and physiology Nature Communications
    Xaquin Castro Dopico, Marina Evangelou, Ricardo C. Ferreira, Hui Guo, Marcin L. Pekalski, …, Andrew M. Prentice, Anette-G. Ziegler, Ezio Bonifacio, Chris Wallace, John A. Todd

2014

1. A Genome-Wide Assessment of the Role of Untagged Copy Number Variants in Type 1 Diabetes PLoS Genetics
   Manuela Zanda, Suna Onengut-Gumuscu, Neil Walker, Corina Shtir, Daniel Gallo, …, Deborah Smyth, John A. Todd, Matthew E. Hurles, Vincent Plagnol, Stephen S. Rich

2. A Method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations Genetic Epidemiology
   Marina Evangelou, Deborah J. Smyth, Mary D. Fortune, Oliver S. Burren, Neil M. Walker, …, Wei‐Min Chen, Patrick Concannon, Stephen S. Rich, John A. Todd, Chris Wallace

3. A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples BMC Genomics
   Nikolas Pontikos, Deborah J Smyth, Helen Schuilenburg, Joanna MM Howson, Neil M Walker, …, Wei Jiang, James A Traherne, John Trowsdale, John A Todd, Chris Wallace

4. A type I Interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes Diabetes
   Ricardo C. Ferreira, Hui Guo, Richard M.R. Coulson, Deborah J. Smyth, Marcin L. Pekalski, …, Linda S. Wicker, John A. Todd, Ezio Bonifacio, Chris Wallace, Anette-G. Ziegler

5. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics PLoS Genetics
   Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt, Lude Franke, Aroon D. Hingorani, Chris Wallace, Vincent Plagnol

6. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations The American Journal of Human Genetics
   Santhi K. Ganesh, Daniel I. Chasman, Martin G. Larson, Xiuqing Guo, Germain Verwoert, …, Cornelia van Duijn, Myriam Fornage, Daniel Levy, Bruce M. Psaty, Aravinda Chakravarti

7. Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes Clinical and Experimental Immunology
   W S Thompson, M L Pekalski, H Z Simons, D J Smyth, X Castro-Dopico, …, M Peakman, C Wallace, L S Wicker, J A Todd, R C Ferreira

8. Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients Diabetologia
   Kate Downes, M. Loredana Marcovecchio, Pamela Clarke, Jason D. Cooper, Ricardo C. Ferreira, …, Helen E. Stevens, Neil M. Walker, Chris Wallace, David B. Dunger, John A. Todd

9. Single nucleotide polymorphisms with Cis-regulatory effects on long non-coding transcripts in human primary monocytes PLoS ONE
   Jonas Carlsson Almlöf, Per Lundmark, Anders Lundmark, Bing Ge, Tomi Pastinen, …, Alison H. Goodall, François Cambien, Panos Deloukas, Willem H. Ouwehand, Ann-Christine Syvänen

10. VSEAMS: A pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes Bioinformatics
    Oliver S. Burren, Hui Guo, Chris Wallace

2013

1. Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors. The Journal of Immunology
   Marcin L Pekalski, Ricardo C Ferreira, Richard M R Coulson, Antony J Cutler, Hui Guo, …, David B Dunger, Chris Wallace, Timothy I M Tree, John A Todd, Linda S Wicker

2. Novel Loci Associated with Increased Risk of Sudden Cardiac Death in the Context of Coronary Artery Disease PLoS ONE
   Adriana Huertas-Vazquez, Christopher P. Nelson, Xiuqing Guo, Kyndaron Reinier, Audrey Uy-Evanado, …, Jonathan Jui, Jerome I. Rotter, Christine M. Albert, Nilesh J. Samani, Sumeet S. Chugh

3. Statistical testing of shared genetic control for potentially related traits Genetic Epidemiology
   Chris Wallace

2012

1. Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genetics
   The Wellcome Trust Case Control Consortium, Julian B Maller, Gilean McVean, Jake Byrnes, Damjan Vukcevic, …, Nilesh J Samani, Stephen C L Gough, Mark I McCarthy, Panagiotis Deloukas, Peter Donnelly

2. Seven newly identified loci for autoimmune thyroid disease. Human Molecular Genetics
   Jason D. Cooper, Matthew J. Simmonds, Neil M. Walker, Oliver Burren, Oliver J. Brand, …, Gillian Coleman, Wellcome Trust Case Control Consortium, Jayne A. Franklyn, John A. Todd, Stephen C.L. Gough

3. Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. European Heart Journal
   Aspasia Angelakopoulou, Tina Shah, Reecha Sofat, Sonia Shah, Diane J. Berry, …, Jackie Price, Richard W. Morris, Shu Ye, Juan P. Casas, Aroon D. Hingorani

4. Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression. PLoS ONE
   Nicolas Greliche, Tanja Zeller, Philipp S. Wild, Maxime Rotival, Arne Schillert, …, Alison H. Goodall, Laurence Tiret, Stefan Blankenberg, David-Alexandre Trégouët, Cardiogenics Consortium

5. Extra-binomial variation approach for analysis of pooled DNA sequencing data Bioinformatics
   Xin Yang, John A. Todd, David Clayton, Chris Wallace

6. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis Nature Genetics
   Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Steve Eyre, Wellcome Trust Case Control Consortium, John Bowes, Dorothée Diogo, …, Robert M Plenge, Soumya Raychaudhuri, Lars Klareskog, Peter K Gregersen, Jane Worthington

7. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease Nature
   The International IBD Genetics Consortium (IIBDGC), Luke Jostins, Stephan Ripke, Rinse K. Weersma, Richard H. Duerr, …, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C. Barrett, Judy H Cho

8. Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene Human Molecular Genetics
   Lucy J. Davison, Chris Wallace, Jason D. Cooper, Nathan F. Cope, Nicola K. Wilson, …, Karl Lackner, Stefan Blankenberg, Peter Fraser, Berthold Gottgens, John A. Todd

9. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations Nature Genetics
   The KidneyGen Consortium, Yukinori Okada, The CKDGen Consortium, The GUGC consortium, Xueling Sim, …, Jiang He, Yuan-Tsong Chen, Yoon Shin Cho, E-Shyong Tai, Toshihiro Tanaka

10. Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes Human Molecular Genetics
    Chris Wallace, Maxime Rotival, Jason D. Cooper, Catherine M. Rice, Jennie H.M. Yang, …, The Cardiogenics Consortium, Laurence Tiret, John A. Todd, David G. Clayton, Stefan Blankenberg

2011

1. Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nature Genetics
   Spanish Consortium on the Genetics of Coeliac Disease (CEGEC), Gosia Trynka, PreventCD Study Group, Wellcome Trust Case Control Consortium (WTCCC), Karen A Hunt, …, Jeffrey C Barrett, Vincent Plagnol, Panos Deloukas, Cisca Wijmenga, David A van Heel

2. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genetics
   Chris Cotsapas, Benjamin F. Voight, Elizabeth Rossin, Kasper Lage, Benjamin M. Neale, …, John A. Todd, David A. Hafler, Stephen S. Rich, Mark J. Daly, on behalf of the FOCiS Network of Consortia

3. An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes. Diabetes
   Austin D.-E. Swafford, Joanna M.M. Howson, Lucy J. Davison, Chris Wallace, Deborah J. Smyth, Helen Schuilenburg, Meeta Maisuria-Armer, Trupti Mistry, Michael J. Lenardo, John A. Todd

4. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. The Lancet
   Muredach P Reilly, Mingyao Li, Jing He, Jane F Ferguson, Ioannis M Stylianou, …, Robert Roberts, Sekar Kathiresan, Nilesh J Samani, Stephen E Epstein, Daniel J Rader

5. Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1 The American Journal of Human Genetics
   Matthew J. Bown, Gregory T. Jones, Seamus C. Harrison, Benjamin J. Wright, Suzannah Bumpstead, …, John R. Thompson, Steve E. Humphries, Robert D. Sayers, Panos Deloukas, Nilesh J. Samani

6. Blood pressure loci identified with a gene-centric array The American Journal of Human Genetics
   Toby Johnson, Tom R. Gaunt, Stephen J. Newhouse, Sandosh Padmanabhan, Maciej Tomaszewski, …, Martin Farrall, Aroon D. Hingorani, Nilesh J. Samani, Mark J. Caulfield, Patricia B. Munroe

7. Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes Diabetes/Metabolism Research and Reviews
   Nada M. Saleh, Srilakshmi M. Raj, Deborah J. Smyth, Chris Wallace, Joanna M. M. Howson, Louise Bell, Neil M. Walker, Helen E. Stevens, John A. Todd

8. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases PLoS Genetics
   Vincent Plagnol, Joanna M. M. Howson, Deborah J. Smyth, Neil Walker, Jason P. Hafler, …, Matthew J. Simmonds, Type 1 Diabetes Genetics Consortium, Polly J. Bingley, Stephen C. Gough, John A. Todd

9. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma Nature Genetics
   Alcohol Genome-wide Association (AlcGen) Consortium, John C Chambers, Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study, Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Global Lipids Genetics Consortium, …, Eric E Schadt, James Scott, Marjo-Riitta Järvelin, Paul Elliott, Jaspal S Kooner

10. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure Nature Genetics
    LifeLines Cohort Study, Louise V Wain, EchoGen consortium, AortaGen Consortium, CHARGE Consortium Heart Failure Working Group, …, Mark J Caulfield, Dabeeru C Rao, Martin D Tobin, Paul Elliott, Cornelia M van Duijn

11. Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes Diabetes
    Jason D. Cooper, Deborah J. Smyth, Neil M. Walker, Helen Stevens, Oliver S. Burren, …, Timothy D. Spector, Willem H. Ouwehand, Thomas J. Wang, Klaus Badenhoop, John A. Todd

12. Large-scale gene-centric analysis identifies novel variants for coronary artery disease PLoS Genetics
    The IBC 50K CAD Consortium

13. Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height The American Journal of Human Genetics
    Matthew B. Lanktree, Yiran Guo, Muhammed Murtaza, Joseph T. Glessner, Swneke D. Bailey, …, Garret A. FitzGerald, Alex Reiner, Robert A. Hegele, Hakon Hakonarson, Brendan J. Keating

2010

1. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature
   Cardiogenics Consortium, Matthias Heinig, Enrico Petretto, Chris Wallace, Leonardo Bottolo, …, Francois Cambien, David Clayton, John A. Todd, Norbert Hubner, Stuart A. Cook

2. Reduced expression of IFIH1 is protective for type 1 diabetes. PLoS ONE
   Kate Downes, Marcin Pekalski, Karen L. Angus, Matthew Hardy, Sarah Nutland, Deborah J. Smyth, Neil M. Walker, Chris Wallace, John A. Todd

3. Genetic loci influencing kidney function and chronic kidney disease Nature Genetics
   John C Chambers, Weihua Zhang, Graham M Lord, Pim van der Harst, Debbie A Lawlor, …, Liz Lightstone, James Scott, Gerjan Navis, Paul Elliott, Jaspal S Kooner

4. Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls Nature
   The Wellcome Trust Case Control Consortium

5. The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes Nature Genetics
   Chris Wallace, Deborah J Smyth, Meeta Maisuria-Armer, Neil M Walker, John A Todd, David G Clayton

2009

1. Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS ONE
   Ilja M. Nolte, Chris Wallace, Stephen J. Newhouse, Daryl Waggott, Jingyuan Fu, …, Mark Caulfield, Harold Snieder, Andrew D. Paterson, Patricia B. Munroe, Yalda Jamshidi

2. Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. PLoS ONE
   Stephen Newhouse, Martin Farrall, Chris Wallace, Mimoza Hoti, Beverley Burke, …, Meena Kumari, Michael Marmot, Eric Brunner, Mark Caulfield, Patricia B. Munroe

3. Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution PLoS Genetics
   Cecilia M. Lindgren, Iris M. Heid, Joshua C. Randall, Claudia Lamina, Valgerdur Steinthorsdottir, …, Ruth J. F. Loos, Kari Stefansson, Karen L. Mohlke, Inês Barroso, Mark I. McCarthy for the GIANT consortium

4. Genome-wide association study identifies eight loci associated with blood pressure Nature Genetics
   Wellcome Trust Case Control Consortium, Christopher Newton-Cheh, Toby Johnson, Vesela Gateva, Martin D Tobin, …, Ruth JF Loos, Paul Elliott, Gonçalo R Abecasis, Mark Caulfield, Patricia B Munroe

5. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations PLoS Genetics
   Melanie Kolz, Toby Johnson, Serena Sanna, Alexander Teumer, Veronique Vitart, …, Peter Vollenweider, Mark Caulfield, for the WTCCC, Thomas Illig, Christian Gieger

6. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Nature Genetics
   the GIANT Consortium

2008

1. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genetics
   The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Ruth J F Loos, KORA, Nurses’ Health Study, Diabetes Genetics Initiative, …, Vincent Mooser, Panos Deloukas, Mark I McCarthy, Nicholas J Wareham, Inês Barroso

2. Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses PLoS ONE
   Vincent Plagnol, Elif Uz, Chris Wallace, Helen Stevens, David Clayton, Tayfun Ozcelik, John A. Todd

3. Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia The American Journal of Human Genetics
   Chris Wallace, Stephen J. Newhouse, Peter Braund, Feng Zhang, Martin Tobin, …, Martin Farrall, Tim Spector, Nilesh J. Samani, Mark J. Caulfield, Patricia B. Munroe

4. Genome-wide association analysis identifies 20 loci that influence adult height Nature Genetics
   Diabetes Genetics Initiative, Michael N Weedon, The Wellcome Trust Case Control Consortium, Cambridge GEM Consortium, Hana Lango, …, Mark Caulfield, Patricia B Munroe, Andrew T Hattersley, Mark I McCarthy, Timothy M Frayling

5. Glutathione S-transferase variants and hypertension Journal of Hypertension
   Christian Delles, Sandosh Padmanabhan, Wai Kwong Lee, William H Miller, Martin W McBride, …, Patricia B Munroe, Martin Farrall, John Webster, John M Connell, Anna F Dominiczak

6. SLC2A9 is a high-capacity urate transporter in humans PLoS Medicine
   Mark J Caulfield, Patricia B Munroe, Deb O’Neill, Kate Witkowska, Fadi J Charchar, …, Chen Ji, Roberto Iacone, Pasquale Strazzullo, Kelle H Moley, Chris Cheeseman

2007

1. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics
   Wellcome Trust Case Control Consortium, The Australo-Anglo-American Spondylitis Consortium (TASC)

2. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nature Genetics
   Genetics of Type 1 Diabetes in Finland, John A Todd, the Wellcome Trust Case Control Consortium, Neil M Walker, Jason D Cooper, …, Joanne M Heward, Stephen C L Gough, David B Dunger, Linda S Wicker, David G Clayton

3. Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension Journal of Medical Genetics
   Ana Carolina Braga Marçano, Beverley Burke, Johannie Gungadoo, Chris Wallace, Pamela J Kaisaki, …, Mark Lathrop, Mark Caulfield, Nilesh Samani, Dominique Gauguier, Patricia B Munroe

4. Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates Genome Research
   Chris Wallace, Richard J. Dobson, Patricia B. Munroe, Mark J. Caulfield

5. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A Nature
   The Wellcome Trust Case Control Consortium, Sergey Nejentsev, Joanna M. M. Howson, Neil M. Walker, Jeffrey Szeszko, …, Jason D. Cooper, Gloria Ribas, R. Duncan Campbell, David G. Clayton, John A. Todd

6. Rheumatoid arthritis association at 6q23 Nature Genetics
   Wellcome Trust Case Control Consortium, Wendy Thomson, YEAR Consortium, Anne Barton, Xiayi Ke, …, David M Reid, Paul Wordsworth, Pille Harrison, David Strachan, Jane Worthington

2006

1. Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. The American Journal of Human Genetics
   Chris Wallace, Ming-Zhan Xue, Stephen J. Newhouse, Ana Carolina B. Marçano, Abiodun K. Onipinla, …, Charles Mein, Nilesh J. Samani, Mark J. Caulfield, David G. Clayton, Patricia B. Munroe

2. Chromosome 2p shows significant linkage to antihypertensive response in the British Genetics of Hypertension Study. Hypertension
   Sandosh Padmanabhan, Chris Wallace, Patricia B. Munroe, Richard Dobson, Morris Brown, …, John Webster, Mark Lathrop, Mark Caulfield, Anna F. Dominiczak, John M. Connell

3. Appropriate use of information on family history of disease in recruitment for linkage analysis studies Annals of Human Genetics
   C. Wallace, D.G. Clayton

4. Haplotypes of the beta-2 adrenergic receptor associate with high diastolic blood pressure in the Caerphilly prospective study Journal of Hypertension
   Alexander Binder, Edwin Garcia, Chris Wallace, Kazeem Gbenga, Yoav Ben-Shlomo, …, Philippa Brown, Mark Caulfield, Falko Skrabal, Peter Kotanko, Patricia Munroe

5. Improved power offered by a score test for linkage disequilibrium mapping of quantitative-trait loci by selective genotyping The American Journal of Human Genetics
   Chris Wallace, Juliet M. Chapman, David G. Clayton

6. Increased support for linkage of a novel locus on chromosome 5q13 for essential hypertension in the British Genetics of Hypertension Study Hypertension
   Patricia B. Munroe, Chris Wallace, Ming-Zhan Xue, Ana Carolina B. Marçano, Richard J. Dobson, …, John Webster, David Clayton, Martin Farrall, Charles A. Mein, Mark Caulfield

7. Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension Human Molecular Genetics
   Jordana Tzenova Bell, Chris Wallace, Richard Dobson, Steven Wiltshire, Charles Mein, …, G. Mark Lathrop, John Connell, Patricia Munroe, Mark Caulfield, Martin Farrall

2005

1. Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study Human Molecular Genetics
   Stephen J. Newhouse, Chris Wallace, Richard Dobson, Charles Mein, Janine Pembroke, …, John M. Connell, John Webster, G. Mark Lathrop, Mark Caulfield, Patricia B. Munroe

2004

1. Linkage analysis of susceptibility to leprosy type using an IBD regression method Genes & Immunity
   C Wallace, J Fitness, B Hennig, L Sichali, L Mwaungulu, JM Pönnighaus, DK Warndorff, D Clayton, PEM Fine, AVS Hill

2003

1. Estimating the relative recurrence risk ratio using a global cross-ratio model. Genetic Epidemiology
   Chris Wallace, David Clayton

2. Trends in drug overdose deaths in England and Wales 1993-98: Methadone does not kill more people than heroin Addiction
   Matthew Hickman, Peter Madden, John Henry, Allan Baker, Chris Wallace, Jon Wakefield, Gerry Stimson, Paul Elliott